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Designing Microscopy Experiments Related To Infectious Diseases And Antivirals

Written By: Heather Brown-Harding, PhD The novel coronavirus (SARS-CoV-2) emerged in Wuhan, China, in December 2019  and spread across the globe becoming the pandemic that the world is reeling with today. Currently, COVID-19  has no targeted therapies approved by the...

Getting A New Flow Cytometer? Try Before You Buy (And 2 Other Tips)

Written By: Tim Bushnell, PhD One question that I get asked on a regular basis is what flow cytometer should I purchase?  It’s not as simple as you might imagine. In fact, you need to treat this process as carefully...

My 3-Step Panel Validation Pocket Guide

Written By: Tim Bushnell, PhD Experimental validation refers to the process of evaluating a panel and ensuring it’s robust. Sometimes, you're just handed a panel that you have to follow, and it might not be the best panel for your...

Easy-To-Forget Flow Fundamentals That Thwart Bad Science

Written By: Tim Bushnell, PhD No matter how advanced or cutting-edge your study is, good science is profoundly dependent on the fundamentals. In fact, no matter your experience level, it is always good to revisit the fundamentals now and again....

Important Controls For Your Flow Cytometry Lab

Written By: Tim Bushnell, PhD No researcher wants to discover that the results of a long, careful experiment are confounded by an uncontrolled variable. To assist in data interpretation, you must build careful controls into your experimental workflow. These controls...

4 Factors To Improve Flow Cytometry Cell Sorting Speed

Written By: Tim Bushnell, PhD Cell sorting owes a lot to Mack Fuwyler  - when he developed the first cell sorter, he started a revolution. Finally, researchers had a tool to isolate specific cells of interest. In the intervening years,...

Optical Tissue Clearing For Pristine Sample Preparation

Optical tissue clearing is an essential step in high-resolution microscopy. Heather-Brown Harding, PhD, discusses the available techniques. Imaging deep into tissues has always been difficult, whether challenges derive from working distance, light absorption by natural chromophores, or light scattering by...

4 Flow Cytometry Assays For Monitoring Intracellular Processes

Written By: Tim Bushnell, PhD The most common flow assay is undoubtedly immunophenotyping, in which fluorescently tagged antibodies are used to bind to cellular proteins. This allows you to determine the types of cells present. As long as there is...

Discover The Myriad Applications Of Beads In Flow Cytometry

What is the single-most important feature of a flow cytometry experiment? Arguably, it’s the stained cells that gather data about biological processes of interest. However, a flow cytometer can measure cell-like particles as well as cells, which opens the realm...

Books

Advanced Microscopy

Learn the best practices and advanced techniques across the diverse fields of microscopy, including instrumentation, experimental setup, image analysis, figure preparation, and more.

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flow cytometry tablet eBook cover

Modern Flow Cytometry

Learn the best practices of flow cytometry experimentation, data analysis, figure preparation, antibody panel design, instrumentation and more. 

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Advanced 4-10 Color Compensation

Advanced 4-10 Color Compensation, Learn strategies for designing advanced antibody compensation panels and how to use your compensation matrix to analyze your experimental data.

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